Comet Calendar
Green Systems Biology Seminars Fall 2024 - Dr. Michael Levine
Wednesday, October 30, 2024 10am to 11am
Event Details
Join us on October 30, 2024, as we welcome Dr. Michael Levine from Princeton University! He will be joining us for the Green Systems Biology Seminars.
Dr. Levine will present a lecture titled Meta-loops in the Drosophila Brain and Neural Crest Lineage in the Ciona Tadpole. 'Long-range enhancer-promoter interactions depend on two architectural elements in the Drosophila genome: boundaries and tethering elements. These produce precise and timely activation of segmentation genes and Hox Genes in the Drosophila embryo. Micro-C XL assays identified hundreds of regulatory loops in the Drosophila brain formed by tether-tether interactions. These elements are in ultra-long-range interactions spanning 2-20 megabases across chromosome arms. I will discuss the possibility that variable folding of meta-loops could be a source of stochastic gene expression in the CNS.
The neural crest is the most striking innovation of the vertebrate embryo, but its origin remains uncertain. Previous studies identified two potential neural crest lineages (a8.25 and b8.18) in the Ciona tadpole. However, there is recent evidence that the BTNs-derivatives of b8.18-correspond to placode-derived cranial ganglia. By contrast, lineage tracing studies identify pigment cells and neural stem-like cells as derivatives of a8.25, suggesting multipotency, a key property of vertebrate neural crest,"
Date: Wednesday, October 30, 2024
Time: 10 AM
Where: TI Auditorium - ECSS 2.102
Host: Dr. Chen Cao, Ph.D.
Location
Texas Instruments Auditorium (ECSS 2.102)
800 W. Campbell Road, Richardson, Texas 75080-3021
Department
- Erik Jonsson School of Engineering and Computer Science
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Contact Information
- Dr. Chen Cao
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