The Department of Chemistry and Biochemistry will be holding seminar series every Friday between 3:30pm-4.30pm starting on Sep 3rd (second week of the semester). The seminars will be presented either virtually via BbCollaborate or in person (Room SCI 1.210).

The speaker is Dr. Randy Stockbridge from University of Michigan. This seminar will be delivered in virtual and hosted by Dr. Hedieh Torabifard. The link can be provided upon request (please contact Dr. Gabriele Meloni at gabriele.meloni@utdallas.edu).

Title: The molecular basis for antiseptic resistance in bacteria

Abstract: By providing broad resistance to ubiquitous disinfectants and antiseptics and other environmental biocides, transporters from the small multidrug resistance (SMR) family drive the spread of multidrug resistance cassettes among bacterial populations. A fundamental understanding of substrate selectivity by SMR transporters is needed to identify the types of selective pressures that contribute to this process. In this talk, I will describe the molecular basis for the recognition of diverse substrates by SMR proteins, revealed through a combination of x-ray crystallography and electrophysiological approaches. 

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