BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:Statistics Seminar by Peifeng Ruan (UTSW)
X-WR-TIMEZONE:Central Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260721T020730Z
UID:tag:localist.com\,2008:EventInstance_42951359168457
DTSTART:20230505T160000Z
DTEND:20230505T170000Z
DESCRIPTION:A multi-use graph neural network framework for single-cell mult
 i-omics data\n\nThe advances of single-cell multi-omics profiling technolo
 gies in biomedical research offer an unprecedent opportunity for understan
 ding cell heterogeneity and subpopulations. There are many statistical and
  computational challenges in the integrative analyses of these rich data\,
  including sequencing sparsity\, complex differential patterns in gene exp
 ression\, and different platforms and panels used to generate multiple sin
 gle-cell multi-omics. In this presentation\, we introduce a multi-use grap
 h neural network framework that can effectively impute and predict missing
  sequencing panels\, integrate multi-omics single-cell datasets\, and form
 ulate and aggregate cell–cell relationships with graph neural networks. 
 Comprehensive simulations and applications on multiple single multi-omics 
 datasets demonstrate that our proposed method is a powerful tool for gener
 al single-cell data multi-omics analyses that outperforms the existing met
 hods for protein prediction\, gene imputation and cell clustering.
GEO:32.989016;-96.750277
LOCATION:Sciences Building (SCI)\, 2.210
SUMMARY:Statistics Seminar by Peifeng Ruan (UTSW)
URL;VALUE=URI:https://calendar.utdallas.edu/event/statistics_seminar_by_pei
 feng_ruan_utsw
CATEGORIES:Lectures & Workshops
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